Trifluoromethanesulfonic Anhydride, CAS number 358-23-6, is a highly reactive and specialized chemical compound with a wide range of applications in organic synthesis and materials science. It belongs to the class of sulfonyl anhydrides, a group of compounds characterized by their ability to act as powerful acylating and sulfonating agents.
Chemical Properties:CAS Number: 358-23-6
Molecular Formula: CF₃SO₂OSO₂CF₃
Molecular Weight: 254.07 g/mol
Appearance: Typically a colorless to pale yellow liquid with a pungent odor.
Stability: Highly reactive and moisture-sensitive. It must be handled under strictly controlled conditions to prevent decomposition or violent reactions.
Applications of Trifluoromethanesulfonic Anhydride, CAS 358-23-6:Organic Synthesis: Trifluoromethanesulfonic anhydride serves as an important intermediate and reagent in the synthesis of complex organic molecules. Its strong sulfonylating ability allows it to modify various functional groups, particularly alcohols and amines, converting them into trifluoromethylsulfonates, which are valuable intermediates in organic chemistry.
Polymer Chemistry: Due to its reactivity, it finds use in the modification of polymers, enabling the introduction of trifluoromethylsulfonyl groups, which can impart unique properties such as improved thermal stability, chemical resistance, or surface properties.
Pharmaceuticals: In the pharmaceutical industry, trifluoromethanesulfonic anhydride is used as a reagent in the synthesis of certain bioactive molecules, particularly those requiring trifluoromethylsulfonyl substitution for enhanced biological activity or selectivity.
Materials Science: It has applications in the development of advanced materials, including those with tailored surface properties or improved performance in specific environments.
